Available for Android and iOS devices. Chest 113 (1998): 1272-6, 23. Fluticasone Propionate/Salmeterol Side Effects See also Precautions section. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. [Ref], Very common (10% or more): Upper respiratory tract infections (up to 27%), pharyngitis (up to 13%), nasopharyngitis, Common (1% to 10%): Pneumonia, bronchitis, throat irritation, hoarseness, dysphonia, sinusitis, upper respiratory inflammation, viral respiratory infections, cough, rhinorrhea/postnasal drip, epistaxis, nasal congestion/blockage, laryngitis, unspecified oropharyngeal plaques, dryness of nose, lower respiratory signs and symptoms, lower respiratory infections, lower respiratory hemorrhage, congestion, Rare (less than 0.1%): Oropharyngeal angioedema, bronchospasm, paradoxical bronchospasm, Frequency not reported: Nose, and throat infections, laryngitis, nasal sinus disorders, nasal sinus disorders, Postmarketing reports: Paranasal sinus pain, rhinitis, throat soreness, tonsillitis, asthma, asthma exacerbation, chest congestion, chest tightness, tracheitis, wheezing, report of upper respiratory symptoms of laryngeal spasm, irritation, or swelling such as stridor or chocking[Ref], Common (1% to 10%): Palpitations, tachycardia, arrhythmias, myocardial infarction, postoperative complications, Uncommon (0.1% to 1%): Atrial fibrillation, angina pectoris, Rare (less than 0.1%): Cardiac arrhythmias (including supraventricular tachycardia and extrasystoles), Postmarketing reports: Ventricular tachycardia, pallor[Ref], Common (1% to 10%): Contusions, wounds, eczema, dermatitis, dermatosis, Frequency not reported: Skin flakiness and acquired ichthyosis, disorders of sweat and sebum, Postmarketing reports: Ecchymoses, photodermatitis[Ref], Common (1% to 10%): Oral and throat candidiasis, nausea and vomiting, gastrointestinal discomfort and pain, dental discomfort and pain, hyposalivation, gastrointestinal infections, disorders of hard tissue of teeth, abdominal discomfort and pain, oral abnormalities, gastrointestinal discomfort and pain, viral gastrointestinal infections, diarrhea, Rare (less than 0.1%): Esophageal candidiasis, Postmarketing reports: Oral ulcerations, dyspepsia, xerostomia[Ref], Common (1% to 10%): Allergies and allergic reactions[Ref], Common (1% to 10%): Hypokalemia, weight gain, Frequency not reported: Fluid retention[Ref], Common (1% to 10%): Muscle cramps, traumatic fractures, arthralgia, myalgia, arthralgia, articular rheumatism, muscle spasms, musculoskeletal inflammation, bone and skeletal pain, muscle injuries, soft tissue injuries, Postmarketing reports: Muscle stiffness, tightness and rigidity, bone and cartilage disorders, myositis, osteoporosis, fractures[Ref], Common (1% to 10%): Allergic eye disorders, eye edema and swelling, Frequency not reported: Dry eyes, eye infections, keratitis, conjunctivitis[Ref], Common (1% to 10%): Candidiasis unspecified site, ear signs and symptoms, viral infections, bacterial infections, inflammation, bacterial reproductive infections, Rare (less than 0.1%): Angioedema, facial angioedema, Frequency not reported: Syncope, edema and swelling, dysmenorrhea, pain, unusual taste, lacerations, Postmarketing reports: Ear ache, fever[Ref], Uncommon (0.1% to 1%): Cutaneous hypersensitivity reactions, Rare (less than 0.1%): Anaphylactic reactions including anaphylactic shock[Ref], Uncommon (0.1% to 1%): Anxiety, sleep disorders, Rare (less than 0.1%): Behavioral changes, including psychomotor hyperactivity and irritability (predominately in children), Frequency not reported: Depression, aggression (predominantly in children), Rare (less than 0.1%): Cushing's syndrome, Cushingoid features, adrenal suppression, growth retardation in children and adolescents, decrease bone mineral density, Postmarketing reports: Hypercorticism[Ref], Frequency not reported: Abnormal liver function tests[Ref], 1. In most cases, salmeterol side effects are minor and either do not require treatment or can easily be treated. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. "Product Information. Br J Clin Pharmacol 37 (1994): 199-204, 25. Ullman A, Svedmyr N "Salmeterol comparison with salbutamol in adult asthmatic patients." Executive Committee American Academy of Allergy and Immunology "Inhaled corticosteroids and severe viral infections." Brogden RN, Faulds D "Salmeterol xinafoate. Commonly reported side effects of fluticasone/salmeterol include: upper respiratory tract infection, pneumonia, and headache. Eur Respir J 7 (1994): 2089-90, 17. Maconochie JG, Minton NA, Chilton JE, Keene ON "Does tachyphylaxis occur to the non-pulmonary effects of salmeterol?" Fluticasone can affect growth in children. Applies to fluticasone / salmeterol: inhalation aerosol liquid, inhalation disk, inhalation powder. You may report side effects to Health Canada at 1-866-234-2345. Along with its needed effects, fluticasone/salmeterol may cause some unwanted effects. Lancet 337 (1991): 1169-70, 33. Grahnen A, Eckernas SA, Brundin RM, Lingandersson A "An assessment of the systemic activity of single doses of inhaled fluticasone propionate in healthy volunteers." With any medication, there are risks and benefits. With inhaled fluticasone very little medicine gets into the rest of your body, so it's unlikely to give you side effects. O 0, 9. "Product Information. Advair Diskus (fluticasone-salmeterol)" Glaxo Wellcome, Research Triangle Pk, NC. Certain side effects, however, should … Rinse your mouth with water without swallowing after using ADVAIR HFA to help decrease your chance of getting thrush. It is used by inhaling the medication into the lungs. It is used to treat COPD. Other side effects include: dizziness, myalgia, and nausea. A Common Cold 2. Advair® HFA (fluticasone propionate and salmeterol) Inhalation Aerosol contains 2 medicines and it is very likely that you are experiencing a side effect from 1 and not both. Common side effects of fluticasone/salmeterol include upper respiratory tract infection, throat irritation, hoarseness and voice changes, and thrush in the mouth or throat. JAMA 277 (1997): 722-7, 30. Do NOT use for a COPD attack. There is no incidence of additional adverse events following concurrent administration of the two compounds. See below for a comprehensive list of adverse effects. Below is a summary of known side effects for Fluticasone Propionate and Salmeterol. Booth H, Bish R, Walters J, Whitehead F, Walters EH "Salmeterol tachyphylaxis in steroid treated asthmatic subjects." Common side effects. Mann RD, Kubota K, Pearce G, Wilton L "Salmeterol: a study by prescription-event monitoring in a UK cohort of 15,407 patients." Your child's doctor will monitor your child's growth carefully. Side Effects for WIXELA INHUB (fluticasone propionate and salmeterol powder) are also known as adverse reactions. Read More Nausea and headache have been reported as common side effects of Advair™ Diskus® ( fluticasone propionate and salmeterol ) Inhalation Powder, as has an unpleasant taste or smell. Ann Allergy Asthma Immunol 75 (1995): 243-8, 3. Thorax 43 (1988): 674-8, 22. Br J Clin Pharmacol 43 (1997): 155-61, 36. Drugs 47 (1994): 318-31, 27. Safety in pregnancy and breastfeeding is unclear. Find everything you need to know about Salmeterol (Serevent Diskus), including what it is used for, warnings, reviews, side effects, and interactions. Check with your doctor immediately if any of the following side effects occur while taking fluticasone/salmeterol: Get emergency help immediately if any of the following symptoms of overdose occur while taking fluticasone/salmeterol: Some side effects of fluticasone / salmeterol may occur that usually do not need medical attention. Fluticasone: Protein binding: 91%. Fluticasone and salmeterol side effects. Maconochie JG, Forster JK "Dose-response study with high-dose inhaled salmeterol in healthy subjects." You may report them to the FDA. [Ref], Very common (10% or more): Headache (up to 21%), Postmarketing reports: Paraesthesia, restlessness, compressed nerve syndrome, aphonia[Ref], The incidence of pneumonia was higher in adult subjects with COPD older than 65 years compared with younger subjects with COPD (18% versus 14%). Clark CE, Ferguson AD, Siddorn JA "Respiratory arrests in young asthmatics on salmeterol." Glaxo Wellcome, Research Triangle Park, NC. 5. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Contact your doctor immediately if you experience any of the following: Sudden trouble breathing or choking Fluticasone: Extensive first-pass metabolism by cytochrome CYP3A4. Holliday SM, Faulds D, Sorkin EM "Inhaled fluticasone propionate. Talk with your doctor if you think your child is not growing at a normal rate while using this medication. Advair Diskus and Advair HFA (fluticasone propionate and salmeterol oral inhaler) is a combination of a corticosteroid and a beta2-adrenergic bronchodilator used to treat asthma or chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Clark DJ, Lipworth BJ "Adrenal suppression with chronic dosing of fluticasone propionate compared with budesonide in adult asthmatic patients." Garbe E, LeLorier J, Boivin JF, Suissa S "Inhaled and nasal glucocorticoids and the risks of ocular hypertension or open-angle glaucoma." More common side effects The adult side … Find treatment reviews for Fluticasone-Salmeterol from other patients. 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